The phrase "You only live once" can receive negative perception from some people. But if we look at it from opportunity maximisation point of view, this phrase can apply in a different light.

I only live once,
so I want to enjoy God's love and worship him
so I want to make the best of it for God
so I want to be a blessing for those I love
and when I die
may I look back and be content
that I have led my life for God

~

Related: Store treasures in heaven